-
Alerid Syrup 30ml
KSh 90.00
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Cosatrim DS Tablets 960mg 10's
KSh 100.00
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Atenolol 25mg 28's
KSh 100.00
Nexium 40mg IV 1s
KSh 1,900.00
Nexium 40mg IV effectively lowers gastric acid quickly, making it perfect for patients who cannot take oral medications. The product is a lyophilized powder that requires reconstitution and comes in a single-use vial. Active Substances: Esomeprazole 40 mg per vial.
Acid Reflux
Suggested Use
Nexium 40mg IV is indicated for:
- Gastroesophageal Reflux Disease (GERD): Short-term treatment of erosive esophagitis in patients who cannot take oral therapy.
- Peptic Ulcers: Management of gastric and duodenal ulcers, particularly associated with NSAID use.
- Prevention of Rebleeding in Peptic Ulcers: Following endoscopic hemostasis in bleeding ulcers.
- Zollinger-Ellison Syndrome: Management of pathological hypersecretory conditions.
- Stress Ulcer Prophylaxis: In critically ill patients.
Dosage and Administration
- Adults:
- GERD with Erosive Esophagitis: 40mg once daily via IV injection over 3 minutes or IV infusion over 10–30 minutes.
- Prevention of Rebleeding in Peptic Ulcers: 80mg IV bolus followed by continuous infusion of 8mg/hour for 72 hours.
- Zollinger-Ellison Syndrome: Dose adjusted based on individual response (starting at 40mg twice daily).
- Maximum daily dose: 80mg, with adjustments based on clinical need.
- Reconstitution:
- Dilute with 5ml of 0.9% Sodium Chloride Injection for IV injection.
- For infusion, further dilute in 100ml of compatible IV solution (e.g., 0.9% Sodium Chloride or 5% Dextrose).
Note: Nexium 40mg IV is a prescription-only medication. Always use under the guidance of a healthcare professional.
Warning
- Hypersensitivity: Contraindicated in patients with known hypersensitivity to esomeprazole, other substituted benzimidazoles, or any component of the formulation.
- Gastric Malignancy: Symptom relief does not preclude the presence of gastric cancer; assess patients accordingly.
- Clostridium difficile Infection: Prolonged use may increase the risk of C. difficile-associated diarrhea.
- Bone Fractures: High doses or long-term use may be associated with an increased risk of fractures.
- Hypomagnesemia: Monitor magnesium levels with prolonged therapy or concurrent use of other medications causing hypomagnesemia.
- Vitamin B12 Deficiency: Long-term therapy may lead to reduced absorption of vitamin B12.
- Pregnancy and Lactation: Use only if the potential benefit justifies the risk.
Storage:
- Store below 25 °C.
- Protect from light.
- Use immediately after reconstitution; discard unused solution.
