Glipita M 50/500 Tablet 30’s
KSh 1,400.00
Glipita M 50/500 Tablet is a combination medication for type 2 diabetes management. It contains Sitagliptin (50mg) to boost insulin production and reduce liver glucose, and Metformin Hydrochloride (500mg) to lower glucose production and enhance insulin sensitivity. Together, they effectively control blood sugar levels for patients who have difficulty managing diabetes with diet, exercise, and single-drug therapy.
Anti-Diabetics
Suggested Use
- Management of type 2 diabetes mellitus in adults.
- As an adjunct to diet and exercise.
- In cases where monotherapy with sitagliptin or metformin does not provide adequate glycemic control.
- For patients who are already receiving sitagliptin and metformin as separate tablets to simplify therapy.
Dose adjustments are individualized based on the patient’s current treatment regimen, efficacy, and tolerability.
Warning
- Lactic Acidosis: Rare but serious; monitor for symptoms such as malaise, muscle pain, and difficulty breathing.
- Renal Impairment: Not recommended for patients with eGFR < 30 mL/min/1.73 m².
- Discontinue if pancreatitis is suspected.
- Long-term use of metformin may lead to a decrease in vitamin B12 levels.
- Use cautiously in patients with congestive heart failure due to an increased risk of lactic acidosis.
- Hypoglycemia: Low risk when used alone but may increase when combined with sulfonylureas or insulin.
- Limit alcohol consumption as it increases the risk of lactic acidosis.
- Common Side effects: Nausea, diarrhoea, flatulence, upper respiratory tract infections.
- Rare but Serious: Lactic acidosis, pancreatitis, hypersensitivity reactions.
Contraindications:
- Severe renal impairment (eGFR < 30 mL/min/1.73 m²).
- Acute or chronic metabolic acidosis, including diabetic ketoacidosis.
- Hypersensitivity to sitagliptin, metformin, or any excipients in the formulation.