Class: Antiretrovirals (Anti-infectives)
Mechanism of Action:
Synonym: Azt, Azidothymidine
Molecular Formulae: C10H13N5O4 = 267.2
Precautions: Hypersensitivity. care in anaemia and neutropenia.
Indications/Uses: Nucleoside reverse transcriptase inhibitor used in hiv infection, with other agents; 200mg tid or 300mg bd. prevention of infection after needlesticks.
Interactions: Phenytoin. probenecid. chronic administration of paracetamol.
Side Effects: Severe headache. anaemia. neutrpenia. nausea. vomiting. fever. abdominal pains. myalgia. insomnia. rash.