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Zeptol Cr 300 Tablets


Class: Antiepileptics (CNS agents)

Mechanism of Action:


Synonym:

Molecular Formulae: C15H12N2O = 236.3

Precautions: Caution in blood disorders, renal or hepatic disease. potential for drug interactions. porphyria.

Indications/Uses: Tonic-clonic and partial seizures 200-400mg initially, increased upto 1.2g to suit condition. trigeminal neuralgia 100mg bd increasing upto 1.6g daily. manic de

Interactions: Reduces effect of anticoagulants, corticosteroids, doxycycline. mefloquine antagonises effect.

Side Effects: Mild; dizziness, ataxia, rash, confusion, agitation, visual disturbances. fever. gastro-intestinal upset. edema.

KSh1,270 KSh1,350

INTRODUCTION

ZEPTOL CR 300MG contains carbamazepine which belongs to the group of medicines called anti-convulsants. It is used to treat certain forms of epilepsy and trigeminal neuralgia (painful condition of face). It can also be used to control bipolar disorder if other medicines are not effective. Carbamazepine treats seizure and symptoms of trigeminal neuralgia by inhibiting voltage-dependent sodium channels and preventing action potentials. It is capable of decreasing mania symptoms in bipolar disorder by increasing dopamine turnover and increase GABA transmission.

Prior to the treatment, your doctor may want you to have a several blood tests to find your condition. Inform your doctor, if you have ever had problems with your bone marrow, porphyria or glaucoma before taking this medicine. The most common side effects of taking this medicine are nausea, vomiting, headache, blurred vision and fluid retention. Avoid drinking alcohol or grapefruit juice while taking this medicine, as it may increase your chance of experiencing side effects. ZEPTOL CR 300MG should be used with caution in pregnant, breastfeeding and in elderly patients.

USES OF ZEPTOL CR 300MG

  • Treats epilepsy and trigeminal neuralgia
  • Controls bipolar disorders if other medicines are not effective

HOW ZEPTOL CR 300MG WORKS

Carbamazepine inhibits and prolongs the inactivation of voltage-dependent sodium channels at the synapse by lowering polysynaptic nerve response and inhibiting post-tetanic potentiation. Blockade of sodium channels, decreases the abnormal excitability of neurons and therefore controls seizures.

It acts as a specific analgesic for trigeminal neuralgia, by inhibiting lingual mandibular reflex and by reducing pain caused by stimulation of nerves in the face. It decreases mania symptoms in bipolar disorder by increasing dopamine turnover and GABA transmission.

DIRECTIONS FOR USE

Always take this medicine as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your condition.

SIDE EFFECTS OF ZEPTOL CR 300MG

SERIOUS

  • Allergic reactions (such as rash, blistering of lips, eyes or mouth or skin peeling with fever)
  • Sore mouth or throat, fever
  • Jaundice (yellowing of your skin or whites of your eyes)
  • Muscle pain or joint pain
  • Breathing problems
  • Pain in area near stomach

COMMON

  • Feeling or being sick
  • Dizziness
  • Lack of coordination
  • Bruising or bleeding
  • Fluid retention and swelling
  • Confusion
  • Headache
  • Blurred vision
  • Dry mouth

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