Class: Antiepileptics (CNS agents)
Mechanism of Action:
Molecular Formulae: C15H12N2O = 236.3
Precautions: Caution in blood disorders, renal or hepatic disease. potential for drug interactions. porphyria.
Indications/Uses: Tonic-clonic and partial seizures 200-400mg initially, increased upto 1.2g to suit condition. trigeminal neuralgia 100mg bd increasing upto 1.6g daily. manic de
Interactions: Reduces effect of anticoagulants, corticosteroids, doxycycline. mefloquine antagonises effect.
Side Effects: Mild; dizziness, ataxia, rash, confusion, agitation, visual disturbances. fever. gastro-intestinal upset. edema.