HOW ZEN RETARD 300MG WORKS
Carbamazepine inhibits and prolongs the inactivation of voltage-dependent sodium channels at the synapse by lowering polysynaptic nerve response and inhibiting post-tetanic potentiation. Blockade of sodium channels, decreases the abnormal excitability of neurons and therefore controls seizures.
It acts as a specific analgesic for trigeminal neuralgia, by inhibiting lingual mandibular reflex and by reducing pain caused by stimulation of nerves in the face. It decreases mania symptoms in bipolar disorder by increasing dopamine turnover and GABA transmission.