Class: Antimetabolite Cytotoxics (Oncology & immunosuppression drugs)
Mechanism of Action:
Molecular Formulae: C15H22FN3O6 = 359.4
Precautions: Caution in impaired renal impairment. use under specialist supervision. bone marrow depression.
Indications/Uses: A prodrug of fluorouracil that is converted to 5fu in body tissues. orally active for metastatic breast and colorectal cancer.
Interactions: Leucovorin calcium enhances toxicity.
Side Effects: Diarrhoea. nausea and vomiting. stomatitis. bone marrow depression.