Class: Antiretrovirals (Anti-infectives)
Mechanism of Action:
Indications/Uses: Nucleoside reverse transcriptase inhibitor used in hiv infection, with other agents; 200mg tid or 300mg bd. prevention of infection after needlesticks.
Interactions: May decrease atazanavir therapeutic effect. lopinavir/ritonavir may increase tenofovir plasma levels.
Side Effects: Asthenia,rash,diarrhea, nausea, abdominal pain, vomiting,myalgia,weight loss.