Class: Antifungals (Anti-infectives)
Mechanism of Action:
Molecular Formulae: C47H73NO17 = 924.1
Precautions: Toxicity common when given parenterally. caution in renal impairment. pregnancy and lactation.
Indications/Uses: Systemic fungal infections; iv max 50mg/day over 2-6 hrs
Interactions: Digoxin (increased toxicity) ciclosporin (nephrotoxicity). corticosteroids (hypokalaemia).
Side Effects: Nausea. anorexia. epigastric pain. vomiting. fever. muscle and joints pains. anaemia. hypokalaemia. hypomagnesia. renal toxicity.